Daniel J J Carr Selected Research

Herpetic Keratitis

11/2021	The Durability of Vaccine Efficacy against Ocular HSV-1 Infection Using ICP0 Mutants 0∆NLS and 0∆RING Is Lost over Time.
12/2017	Reply to "Highly Efficacious Novel Vaccine, Humoral Immunity, and Ocular Herpes Simplex Virus 1: Reality or Myth?"
1/2012	PD-L1-expressing dendritic cells contribute to viral resistance during acute HSV-1 infection.
6/2008	Chemical sympathectomy increases susceptibility to ocular herpes simplex virus type 1 infection.
4/2008	An increase in herpes simplex virus type 1 in the anterior segment of the eye is linked to a deficiency in NK cell infiltration in mice deficient in CXCR3.
3/2006	Abnormal immune response of CCR5-deficient mice to ocular infection with herpes simplex virus type 1.
7/2005	Critical role for the oligoadenylate synthetase/RNase L pathway in response to IFN-beta during acute ocular herpes simplex virus type 1 infection.
1/2004	Consequences of CXCL10 and IL-6 induction by the murine IFN-alpha1 transgene in ocular herpes simplex virus type 1 infection.
9/2003	Effect of anti-CXCL10 monoclonal antibody on herpes simplex virus type 1 keratitis and retinal infection.
11/2002	Resistance to ocular herpes simplex virus type 1 infection in IL-12 transgenic mice.

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Daniel J J Carr Research Topics

Disease

57	Infections 12/2022 - 05/2002
11	Herpetic Keratitis 11/2021 - 09/2002
9	Inflammation (Inflammations) 01/2021 - 05/2011
9	Virus Diseases (Viral Diseases) 01/2017 - 10/2002
5	Herpes Simplex 01/2017 - 10/2002
5	Herpes Genitalis (Genital Herpes) 02/2011 - 07/2005
3	Encephalitis (Encephalitis, Rasmussen) 01/2017 - 12/2008
3	Eye Infections 06/2008 - 09/2003
2	Corneal Opacity 01/2021 - 01/2020
2	Blindness (Hysterical Blindness) 01/2019 - 01/2010
2	Herpes Simplex Encephalitis (Herpes Encephalitis) 01/2016 - 05/2005
2	Keratitis 12/2014 - 09/2003
1	Corneal Neovascularization 10/2020
1	Neoplasms (Cancer) 01/2020
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020
1	Alzheimer Disease (Alzheimer's Disease) 01/2020
1	Hypersensitivity (Allergy) 01/2018
1	Herpes Labialis (Fever Blister) 01/2017
1	Malaria 10/2016
1	Nerve Degeneration 10/2016
1	Parasitic Diseases (Parasitic Disease) 10/2016
1	Neurologic Manifestations (Neurological Manifestations) 01/2016
1	Leukostasis 08/2014
1	Macular Degeneration (Age-Related Maculopathy) 01/2014
1	Multiple Sclerosis 01/2014
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2014
1	Edema (Dropsy) 10/2013
1	Viral Encephalitis 03/2013
1	Pseudomonas Infections 10/2012
1	Corneal Diseases (Corneal Disease) 10/2011
1	Bacterial Infections (Bacterial Infection) 01/2010

Drug/Important Bio-Agent (IBA)

15	ChemokinesIBA 10/2020 - 09/2003
14	CytokinesIBA 10/2020 - 04/2005
12	Antiviral Agents (Antivirals)IBA 01/2016 - 07/2002
9	VaccinesIBA 01/2022 - 01/2016
7	Interferon Type IIBA 10/2016 - 10/2002
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 01/2010
4	Neutralizing AntibodiesIBA 12/2022 - 09/2003
4	Proteins (Proteins, Gene)FDA Link 10/2020 - 11/2002
4	Viral AntigensIBA 01/2019 - 09/2003
4	InterferonsIBA 01/2017 - 09/2002
4	Interleukin-6 (Interleukin 6)IBA 10/2016 - 01/2004
3	Retinaldehyde (Retinal)IBA 10/2020 - 09/2003
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2014 - 04/2007
3	Messenger RNA (mRNA)IBA 11/2014 - 11/2002
3	LigandsIBA 01/2012 - 12/2008
3	Chemokine CXCL10IBA 05/2011 - 09/2003
3	eIF-2 Kinase (eIF 2 Kinase)IBA 08/2006 - 02/2005
2	Complement System Proteins (Complement)IBA 01/2021 - 01/2017
2	Attenuated VaccinesIBA 11/2020 - 01/2019
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2020 - 09/2002
2	Caveolin 1IBA 10/2020 - 08/2014
2	SuspensionsIBA 01/2017 - 10/2015
2	AntigensIBA 05/2011 - 01/2010
2	Interferon-gamma (Interferon, gamma)IBA 02/2011 - 09/2002
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2010 - 10/2006
2	Ligases (Synthetase)IBA 04/2007 - 07/2005
2	2',5'-oligoadenylate (PAPAPA)IBA 04/2007 - 07/2005
2	2',5'-Oligoadenylate Synthetase (2',5' Oligoadenylate Synthetase)IBA 08/2006 - 02/2005
2	DNA (Deoxyribonucleic Acid)IBA 01/2006 - 09/2002
2	2-5A-dependent ribonuclease (RNase L)IBA 07/2005 - 02/2005
2	Interferon-betaIBA 08/2003 - 08/2002
2	Interleukin-12 (IL 12)IBA 11/2002 - 05/2002
1	CollagenIBA 01/2021
1	Matrix Metalloproteinases (MMPs)IBA 01/2021
1	EndotoxinsIBA 10/2020
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2020
1	Pharmaceutical PreparationsIBA 01/2020
1	alvocidib (flavopiridol)IBA 01/2020
1	OsteopontinIBA 01/2020
1	CholesterolIBA 01/2020
1	Amyloid (Amyloid Fibrils)IBA 01/2020
1	AP20187IBA 01/2020
1	Cholinergic Agents (Cholinergics)IBA 01/2020
1	Amyloid beta-PeptidesIBA 01/2020
1	preemptIBA 01/2019
1	AntibodiesIBA 01/2019
1	ragweed pollenIBA 01/2018
1	neonatal Fc receptorIBA 01/2017
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2017
1	Interleukin-2 (IL2)IBA 10/2016
1	Antimalarials (Antimalarial Agents)IBA 10/2016
1	Subunit VaccinesIBA 01/2016
1	EicosanoidsIBA 06/2015
1	Calcitonin Gene-Related PeptideIBA 01/2015
1	Substance PIBA 01/2015
1	TubulinIBA 01/2015
1	Concanavalin AIBA 08/2014
1	Fluorescein-5-isothiocyanate (FITC)IBA 08/2014
1	Chemotactic FactorsIBA 08/2014
1	SphingolipidsIBA 01/2014
1	Acyclovir (Aciclovir)FDA LinkGeneric 03/2013
1	Chemokine CXCL1IBA 10/2012
1	Phosphotransferases (Kinase)IBA 10/2011
1	Trans-Activators (Trans-Acting Factor)IBA 10/2011
1	Hormones (Hormone)IBA 02/2011
1	Transcription Factors (Transcription Factor)IBA 09/2009
1	PerforinIBA 09/2009

Therapy/Procedure

1	Denervation 01/2021
1	Therapeutics 01/2020